human GRP Over-expression AAV

Name 
AAV-h-GRP
Cat No 
AAV-210560
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GRP.

AAV-210560
AAV-h-GRP

Ready-to-use AAV expressing Human GRP (gastrin releasing peptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BN; GRP-10; preproGRP; proGRP
Description (Vector)
GRP encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
2922
Gene Name (Vector)
gastrin releasing peptide
Gene Symbol
GRP
HGNC ID
HGNC:4605
ORF Size (aa)
447
RefSeq ID
NM_002091
RefSeq Synonyms
NM_002091, NM_001012513, NM_001012512, BC004488,
Species
human
UniGene ID
Hs.153444

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.