human GPX3 Over-expression AAV

Name 
AAV-h-GPX3
Cat No 
AAV-210460
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GPX3.

AAV-210460
AAV-h-GPX3

Ready-to-use AAV expressing Human GPX3 (glutathione peroxidase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GPx-P; GSHPx-3; GSHPx-P
Description (Vector)
GPX3 product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
Gene ID
2878
Gene Name (Vector)
glutathione peroxidase 3
Gene Symbol
GPX3
HGNC ID
HGNC:4555
ORF Size (aa)
681
ORF Size (bp)
681 bp
RefSeq ID
NM_002084
RefSeq Synonyms
NM_002084, NM_001329790, BC050378, BC035841, BC013601,
Species
human
UniGene ID
Hs.386793

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.