mouse NUP50 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nup50.
shAAV-266224
AAV-m-NUP50-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nup50 (nucleoporin 50). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1700030K07Rik; AI413123; Npap60
Description (Vector)
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
Gene ID
18141
Gene Name (Vector)
nucleoporin 50
Gene Symbol
Nup50
ORF Size (aa)
1401
ORF Size (bp)
1401 bp
RefSeq ID
NM_016714
RefSeq Synonyms
NM_016714, BC065102, BC060234, BC059239,
Species
mouse
UniGene ID
Mm.28379
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.