mouse NUDT15 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nudt15.
shAAV-266181
AAV-m-NUDT15-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nudt15 (nudix (nucleoside diphosphate linked moiety X)-type motif 15). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6530403O17; A730068G11Rik; MTH2
Description (Vector)
Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA.
Gene ID
214254
Gene Name (Vector)
nudix (nucleoside diphosphate linked moiety X)-type motif 15
Gene Symbol
Nudt15
ORF Size (aa)
513
RefSeq ID
NM_172527
RefSeq Synonyms
NM_172527, BC060962,
Species
mouse
UniGene ID
Mm.386852
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.