mouse NPPB shRNA silencing AAV

Name 
AAV-m-NPPB-shRNA
Cat No 
shAAV-266001
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Nppb.

shAAV-266001
AAV-m-NPPB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nppb (natriuretic peptide type B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA408272; BNF; BNP
Description (Vector)
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Gene ID
18158
Gene Name (Vector)
natriuretic peptide type B
Gene Symbol
Nppb
ORF Size (aa)
366
ORF Size (bp)
366 bp
RefSeq ID
NM_008726
RefSeq Synonyms
NM_008726, NM_001287348, BC061165,
Species
mouse
UniGene ID
Mm.2740

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.