mouse NPHP3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nphp3.
shAAV-265983
AAV-m-NPHP3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nphp3 (nephronophthisis 3 (adolescent)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3632410F03Rik; AI550417; C230078J01; D330020E01Rik; pcy
Description (Vector)
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
Gene ID
74025
Gene Name (Vector)
nephronophthisis 3 (adolescent)
Gene Symbol
Nphp3
ORF Size (aa)
3615
ORF Size (bp)
3615 bp
RefSeq ID
NM_028721
RefSeq Synonyms
NM_172460, NM_028721, BC115724,
Species
mouse
UniGene ID
Mm.41274
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.