mouse NOS3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nos3.
shAAV-265940
AAV-m-NOS3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nos3 (nitric oxide synthase 3, endothelial cell). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310065A03Rik; ecNOS; eNOS; Nos-3
Description (Vector)
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets|Function: Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may downregulate eNOS activity by forming heterodimers with isoform 1.
Gene ID
18127
Gene Name (Vector)
nitric oxide synthase 3, endothelial cell
Gene Symbol
Nos3
ORF Size (aa)
3609
ORF Size (bp)
3609 bp
RefSeq ID
NM_008713
RefSeq Synonyms
NM_008713, BC052636,
Species
mouse
UniGene ID
Mm.258415
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.