mouse NOP10 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nop10.
shAAV-265929
AAV-m-NOP10-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nop10 (NOP10 ribonucleoprotein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110036B12Rik; Nola3; NOP10P
Description (Vector)
Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Gene ID
66181
Gene Name (Vector)
NOP10 ribonucleoprotein
Gene Symbol
Nop10
ORF Size (aa)
195
RefSeq ID
NM_025403
RefSeq Synonyms
NM_025403, BC028497,
Species
mouse
UniGene ID
Mm.272346
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.