mouse NFATC4 shRNA silencing AAV

Name 
AAV-m-NFATC4-shRNA
Cat No 
shAAV-265707
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Nfatc4.

shAAV-265707
AAV-m-NFATC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nfatc4 (nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3110041H08Rik; AW107667; AW546455; Nfat3
Description (Vector)
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.
Gene ID
73181
Gene Name (Vector)
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
Gene Symbol
Nfatc4
ORF Size (aa)
2706
ORF Size (bp)
2706 bp
RefSeq ID
NM_023699
RefSeq Synonyms
NM_023699, NM_001168346, BC028928,
Species
mouse
UniGene ID
Mm.27908

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.