mouse NEURL2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Neurl2.
shAAV-265685
AAV-m-NEURL2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Neurl2 (neuralized E3 ubiquitin protein ligase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Neur2; Ozz; Ozz-E3
Description (Vector)
Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).
Gene ID
415115
Gene Name (Vector)
neuralized E3 ubiquitin protein ligase 2
Gene Symbol
Neurl2
ORF Size (aa)
858
RefSeq ID
NM_001082974
RefSeq Synonyms
NM_001082974, BC156597, BC148675,
Species
mouse
UniGene ID
Mm.474586
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.