mouse NEK3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nek3.
shAAV-265651
AAV-m-NEK3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nek3 (NIMA (never in mitosis gene a)-related expressed kinase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.
Gene ID
23954
Gene Name (Vector)
NIMA (never in mitosis gene a)-related expressed kinase 3
Gene Symbol
Nek3
ORF Size (aa)
1530
ORF Size (bp)
1530 bp
RefSeq ID
NM_011848
RefSeq Synonyms
NM_011848, NM_001162947, BC005411,
Species
mouse
UniGene ID
Mm.41413
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.