mouse NDC80 shRNA silencing AAV

Name 
AAV-m-NDC80-shRNA
Cat No 
shAAV-265535
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ndc80.

shAAV-265535
AAV-m-NDC80-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ndc80 (NDC80 kinetochore complex component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610020P18Rik; AV139730; HEC; HEC1; Kntc2
Description (Vector)
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
Gene ID
67052
Gene Name (Vector)
NDC80 kinetochore complex component
Gene Symbol
Ndc80
ORF Size (aa)
1929
ORF Size (bp)
1929 bp
RefSeq ID
NM_023294
RefSeq Synonyms
NM_023294, BC020131,
Species
mouse
UniGene ID
Mm.225956

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.