mouse NCSTN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ncstn.
shAAV-265534
AAV-m-NCSTN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ncstn (nicastrin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9430068N19Rik; AA727311; Aph2; D1Dau13e; Kiaa0253; mKIAA0253; Nct
Description (Vector)
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
Gene ID
59287
Gene Name (Vector)
nicastrin
Gene Symbol
Ncstn
ORF Size (aa)
2127
ORF Size (bp)
2127 bp
RefSeq ID
NM_021607
RefSeq Synonyms
NM_021607, BC019998,
Species
mouse
UniGene ID
Mm.218203
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.