mouse NCOA6 shRNA silencing AAV

Name 
AAV-m-NCOA6-shRNA
Cat No 
shAAV-265523
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ncoa6.

shAAV-265523
AAV-m-NCOA6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ncoa6 (nuclear receptor coactivator 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
83
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AIB3; ASC-2; ASC2; mKIAA0181; Ncoa7; NRC; PRIP; RAP250
Description (Vector)
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.
Gene ID
56406
Gene Name (Vector)
nuclear receptor coactivator 6
Gene Symbol
Ncoa6
ORF Size (aa)
6210
ORF Size (bp)
6210 bp
RefSeq ID
NM_019825
RefSeq Synonyms
NM_019825, NM_001242558, BC083187,
Species
mouse
UniGene ID
Mm.27592

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.