mouse MYD88 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Myd88.
shAAV-265270
AAV-m-MYD88-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Myd88 (myeloid differentiation primary response gene 88). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity).
Gene ID
17874
Gene Name (Vector)
myeloid differentiation primary response gene 88
Gene Symbol
Myd88
ORF Size (aa)
891
ORF Size (bp)
891 bp
RefSeq ID
NM_010851
RefSeq Synonyms
NM_010851, BC058787, BC005591,
Species
mouse
UniGene ID
Mm.213003
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.