mouse MYD116 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ppp1r15a.
shAAV-265268
AAV-m-MYD116-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ppp1r15a (protein phosphatase 1, regulatory (inhibitor) subunit 15A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9630030H21; Gadd34; Myd116
Description (Vector)
Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
Gene ID
17872
Gene Name (Vector)
protein phosphatase 1, regulatory (inhibitor) subunit 15A
Gene Symbol
Ppp1r15a
ORF Size (aa)
1974
ORF Size (bp)
1974 bp
RefSeq ID
NM_008654
RefSeq Synonyms
NM_008654, BC138486, BC138485,
Species
mouse
UniGene ID
Mm.4048
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.