mouse MUC1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Muc1.
shAAV-265183
AAV-m-MUC1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Muc1 (mucin 1, transmembrane). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD227; EMA; Muc-1
Description (Vector)
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack|Function: The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
Gene ID
17829
Gene Name (Vector)
mucin 1, transmembrane
Gene Symbol
Muc1
ORF Size (aa)
1896
ORF Size (bp)
1896 bp
RefSeq ID
NM_013605
RefSeq Synonyms
NM_013605, BC005441,
Species
mouse
UniGene ID
Mm.16193
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.