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mouse MS4A2 shRNA silencing AAV

Name 
AAV-m-MS4A2-shRNA
Cat No 
shAAV-265022
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ms4a2.

shAAV-265022
AAV-m-MS4A2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ms4a2 (membrane-spanning 4-domains, subfamily A, member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Fce1b; Fcer1b; fcERI; FcRB; Fcrbeta; Ms4a1
Description (Vector)
High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.
Gene ID
14126
Gene Name (Vector)
membrane-spanning 4-domains, subfamily A, member 2
Gene Symbol
Ms4a2
ORF Size (aa)
708
ORF Size (bp)
708 bp
RefSeq ID
NM_013516
RefSeq Synonyms
NM_013516, NM_001276330, NM_001276329, NM_001276328, BC139324, BC139323,
Species
mouse
UniGene ID
Mm.329735

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.