mouse MRPL18 shRNA silencing AAV

Name 
AAV-m-MRPL18-shRNA
Cat No 
shAAV-264911
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mrpl18.

shAAV-264911
AAV-m-MRPL18-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mrpl18 (mitochondrial ribosomal protein L18). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1010001C05Rik; C79879; HSPC071; MRP-L18
Description (Vector)
Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA.
Gene ID
67681
Gene Name (Vector)
mitochondrial ribosomal protein L18
Gene Symbol
Mrpl18
ORF Size (aa)
543
RefSeq ID
NM_026310
RefSeq Synonyms
NM_026310, BC011425,
Species
mouse
UniGene ID
Mm.290166

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.