mouse MMS19 shRNA silencing AAV

Name 
AAV-m-MMS19-shRNA
Cat No 
shAAV-264750
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mms19.

shAAV-264750
AAV-m-MMS19-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mms19 (MMS19 (MET18 S. cerevisiae)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2410001K24Rik; 2610042O15Rik; AI316855; C79368; C86341; Mms19l
Description (Vector)
MMS19 may play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation.
Gene ID
72199
Gene Name (Vector)
MMS19 (MET18 S. cerevisiae)
Gene Symbol
Mms19
ORF Size (aa)
3096
ORF Size (bp)
3096 bp
RefSeq ID
NM_028152
RefSeq Synonyms
NM_028152, BC050817,
Species
mouse
UniGene ID
Mm.218940

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.