mouse MME shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mme.
shAAV-264709
AAV-m-MME-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mme (membrane metallo endopeptidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6030454K05Rik; C85356; CALLA; CD10; NEP; SFE
Description (Vector)
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Gene ID
17380
Gene Name (Vector)
membrane metallo endopeptidase
Gene Symbol
Mme
ORF Size (aa)
2253
ORF Size (bp)
2253 bp
RefSeq ID
NM_008604
RefSeq Synonyms
NM_008604, NM_001289463, NM_001289462, BC034092,
Species
mouse
UniGene ID
Mm.296022
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.