mouse MGAT4B shRNA silencing AAV

Name 
AAV-m-MGAT4B-shRNA
Cat No 
shAAV-264591
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mgat4b.

shAAV-264591
AAV-m-MGAT4B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mgat4b (mannoside acetylglucosaminyltransferase 4, isoenzyme B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA407995; GnTIVb
Description (Vector)
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
Gene ID
103534
Gene Name (Vector)
mannoside acetylglucosaminyltransferase 4, isoenzyme B
Gene Symbol
Mgat4b
ORF Size (aa)
891
ORF Size (bp)
891 bp
RefSeq ID
NM_145926
RefSeq Synonyms
NM_145926, BC031613, BC026638,
Species
mouse
UniGene ID
Mm.86759

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.