mouse MFGE8 shRNA silencing AAV

Name 
AAV-m-MFGE8-shRNA
Cat No 
shAAV-264556
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mfge8.

shAAV-264556
AAV-m-MFGE8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mfge8 (milk fat globule-EGF factor 8 protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA408458; AI325141; lactadherin; MFG-E8; Mfgm; MP47; P47; SED1
Description (Vector)
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication|Function: Medin is the main constituent of aortic medial amyloid.
Gene ID
17304
Gene Name (Vector)
milk fat globule-EGF factor 8 protein
Gene Symbol
Mfge8
ORF Size (aa)
1281
ORF Size (bp)
1281 bp
RefSeq ID
NM_008594
RefSeq Synonyms
NM_008594, NM_001045489, BC003904, BC003892,
Species
mouse
UniGene ID
Mm.1451

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.