mouse MED28 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Med28.
shAAV-264457
AAV-m-MED28-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Med28 (mediator complex subunit 28). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1500003D12Rik; AI451633; AU045690; Eg1; FKSG20; magicin
Description (Vector)
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.
Gene ID
66999
Gene Name (Vector)
mediator complex subunit 28
Gene Symbol
Med28
ORF Size (aa)
537
ORF Size (bp)
537 bp
RefSeq ID
NM_025895
RefSeq Synonyms
NM_025895, BC024941,
Species
mouse
UniGene ID
Mm.283045
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.