mouse MED15 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Med15.
shAAV-264442
AAV-m-MED15-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Med15 (mediator complex subunit 15). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A230074L19Rik; AW536074; mPcqap; Pcqap
Description (Vector)
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway.
Gene ID
94112
Gene Name (Vector)
mediator complex subunit 15
Gene Symbol
Med15
ORF Size (aa)
2250
ORF Size (bp)
2250 bp
RefSeq ID
NM_033609
RefSeq Synonyms
NM_033609, NM_001285886, NM_001285884, NM_001040683, BC054779,
Species
mouse
UniGene ID
Mm.208970
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.