mouse MCM2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mcm2.
shAAV-264372
AAV-m-MCM2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mcm2 (minichromosome maintenance complex component 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA959861; AW476101; BM28; CDCL1; Mcmd2; mKIAA0030
Description (Vector)
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
Gene ID
17216
Gene Name (Vector)
minichromosome maintenance complex component 2
Gene Symbol
Mcm2
ORF Size (aa)
2715
ORF Size (bp)
2715 bp
RefSeq ID
NM_008564
RefSeq Synonyms
NM_008564, BC055318,
Species
mouse
UniGene ID
Mm.16711
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.