mouse MBD2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mbd2.
shAAV-264310
AAV-m-MBD2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mbd2 (methyl-CpG binding domain protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MBD2a
Description (Vector)
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemi-methylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. May enhance the activation of some unmethylated cAMP-responsive promoters.
Gene ID
17191
Gene Name (Vector)
methyl-CpG binding domain protein 2
Gene Symbol
Mbd2
ORF Size (aa)
1245
ORF Size (bp)
1245 bp
RefSeq ID
NM_010773
RefSeq Synonyms
NM_010773, NM_001311071, BC046607,
Species
mouse
UniGene ID
Mm.322
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.