mouse MAEA shRNA silencing AAV

Name 
AAV-m-MAEA-shRNA
Cat No 
shAAV-264077
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Maea.

shAAV-264077
AAV-m-MAEA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Maea (macrophage erythroblast attacher). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110030D19Rik; EMP; Gid9
Description (Vector)
Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.
Gene ID
59003
Gene Name (Vector)
macrophage erythroblast attacher
Gene Symbol
Maea
ORF Size (aa)
1191
ORF Size (bp)
1191 bp
RefSeq ID
NM_021500
RefSeq Synonyms
NM_021500, BC058687, BC039054,
Species
mouse
UniGene ID
Mm.281642

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Ad-m-MAEA-shRNA

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.