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mouse LSM10 shRNA silencing AAV

Name 
AAV-m-LSM10-shRNA
Cat No 
shAAV-263923
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Lsm10.

shAAV-263923
AAV-m-LSM10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Lsm10 (U7 snRNP-specific Sm-like protein LSM10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
Gene ID
116748
Gene Name (Vector)
U7 snRNP-specific Sm-like protein LSM10
Gene Symbol
Lsm10
ORF Size (aa)
369
ORF Size (bp)
369 bp
RefSeq ID
NM_138721
RefSeq Synonyms
NM_138721, NM_001163266, BC026476, BC024543,
Species
mouse
UniGene ID
Mm.41865

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.