mouse LRDD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pidd1.
shAAV-263795
AAV-m-LRDD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pidd1 (p53 induced death domain protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1200011D09Rik; AU042446; Lrdd; Pidd
Description (Vector)
Promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. Associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which an important regulator in apoptotic pathways.
Gene ID
57913
Gene Name (Vector)
p53 induced death domain protein 1
Gene Symbol
Pidd1
ORF Size (aa)
2748
ORF Size (bp)
2748 bp
RefSeq ID
NM_022654
RefSeq Synonyms
NM_022654, BC145857,
Species
mouse
UniGene ID
Mm.334321
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.