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mouse LCLAT1 shRNA silencing AAV

Name 
AAV-m-LCLAT1-shRNA
Cat No 
shAAV-263318
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Lclat1.

shAAV-263318
AAV-m-LCLAT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Lclat1 (lysocardiolipin acyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Agpat8; AI181996; Alcat1; Gm91; Lycat
Description (Vector)
Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages.
Gene ID
225010
Gene Name (Vector)
lysocardiolipin acyltransferase 1
Gene Symbol
Lclat1
ORF Size (aa)
1131
ORF Size (bp)
1131 bp
RefSeq ID
NM_001081071
RefSeq Synonyms
NM_001177968, NM_001177967, NM_001081071, BC158079, BC158076, BC150884, BC147499,
Species
mouse
UniGene ID
Mm.329194

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.