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mouse KLRG1 shRNA silencing AAV

Name 
AAV-m-KLRG1-shRNA
Cat No 
shAAV-263021
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Klrg1.

shAAV-263021
AAV-m-KLRG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Klrg1 (killer cell lectin-like receptor subfamily G, member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2F1-Ag; MAFA; MAFA-L
Description (Vector)
Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Gene ID
50928
Gene Name (Vector)
killer cell lectin-like receptor subfamily G, member 1
Gene Symbol
Klrg1
ORF Size (aa)
567
RefSeq ID
NM_016970
RefSeq Synonyms
NM_016970, BC103548, BC103547, BC103546, BC101953,
Species
mouse
UniGene ID
Mm.20434

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.