human GNG5 Over-expression AAV

Name
AAV-h-GNG5

Cat No
AAV-210117

Availability
4-5 weeks

This is an AAV expressing Human GNG5.

AAV-210117

AAV-h-GNG5

Ready-to-use AAV expressing Human GNG5 (G protein subunit gamma 5). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules (Gilman, 1987 (PubMed 3113327); summary by Ahmad et al., 1995) (PubMed 7606925).(supplied by OMIM, Nov 2010)

Gene ID

2787

Gene Name (Vector)

G protein subunit gamma 5

Gene Symbol

GNG5

HGNC ID

HGNC:4408

ORF Size (aa)

207

RefSeq ID

NM_005274

RefSeq Synonyms

NM_005274, BC003563,

Species

human

UniGene ID

Hs.645427

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.