mouse KLB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Klb.
shAAV-262851
AAV-m-KLB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Klb (klotho beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AV071179; betaKlotho
Description (Vector)
Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
Gene ID
83379
Gene Name (Vector)
klotho beta
Gene Symbol
Klb
ORF Size (aa)
3132
ORF Size (bp)
3132 bp
RefSeq ID
NM_031180
RefSeq Synonyms
NM_031180, BC138010, BC138008,
Species
mouse
UniGene ID
Mm.45274
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.