mouse KHDRBS3 shRNA silencing AAV

Name 
AAV-m-KHDRBS3-shRNA
Cat No 
shAAV-262786
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Khdrbs3.

shAAV-262786
AAV-m-KHDRBS3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Khdrbs3 (KH domain containing, RNA binding, signal transduction associated 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Etle; Salp; SLM-2; Slm2; T-STAR
Description (Vector)
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro.
Gene ID
13992
Gene Name (Vector)
KH domain containing, RNA binding, signal transduction associated 3
Gene Symbol
Khdrbs3
ORF Size (aa)
1041
RefSeq ID
NM_010158
RefSeq Synonyms
NM_010158, BC057577, BC031507,
Species
mouse
UniGene ID
Mm.17964

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.