mouse KCNJ2 shRNA silencing AAV

Name
AAV-m-KCNJ2-shRNA

Cat No
shAAV-262659

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Kcnj2.

shAAV-262659

AAV-m-KCNJ2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Kcnj2 (potassium inwardly-rectifying channel, subfamily J, member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IRK1; Kcnf1; Kir2.1

Description (Vector)

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.

Gene ID

16518

Gene Name (Vector)

potassium inwardly-rectifying channel, subfamily J, member 2

Gene Symbol

Kcnj2

ORF Size (aa)

1287

ORF Size (bp)

1287 bp

RefSeq ID

NM_008425

RefSeq Synonyms

NM_008425, BC137842, BC137841,

Species

mouse

UniGene ID

Mm.401443

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.