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mouse KCNJ10 shRNA silencing AAV

Name 
AAV-m-KCNJ10-shRNA
Cat No 
shAAV-262650
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Kcnj10.

shAAV-262650
AAV-m-KCNJ10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Kcnj10 (potassium inwardly-rectifying channel, subfamily J, member 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BIR10; BIRK-1; Kir1.2; Kir4.1
Description (Vector)
KCNJ10 may be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).
Gene ID
16513
Gene Name (Vector)
potassium inwardly-rectifying channel, subfamily J, member 10
Gene Symbol
Kcnj10
ORF Size (aa)
1140
ORF Size (bp)
1140 bp
RefSeq ID
NM_001039484
RefSeq Synonyms
NM_001039484, BC141088,
Species
mouse
UniGene ID
Mm.254563

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.