mouse JMJD5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Kdm8.
shAAV-262521
AAV-m-JMJD5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Kdm8 (lysine (K)-specific demethylase 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3110005O21Rik; Jmjd5
Description (Vector)
Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
Gene ID
77035
Gene Name (Vector)
lysine (K)-specific demethylase 8
Gene Symbol
Kdm8
ORF Size (aa)
1245
ORF Size (bp)
1245 bp
RefSeq ID
NM_029842
RefSeq Synonyms
NM_029842, BC024807,
Species
mouse
UniGene ID
Mm.307239
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.