mouse ITM2C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Itm2c.
shAAV-262480
AAV-m-ITM2C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Itm2c (integral membrane protein 2C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3110038L02Rik; BRI3; Bricd2c; E25; E25C; ITM3
Description (Vector)
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
Gene ID
64294
Gene Name (Vector)
integral membrane protein 2C
Gene Symbol
Itm2c
ORF Size (aa)
810
RefSeq ID
NM_022417
RefSeq Synonyms
NM_022417, BC012952,
Species
mouse
UniGene ID
Mm.29870
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.