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mouse ITGA5 shRNA silencing AAV

Name 
AAV-m-ITGA5-shRNA
Cat No 
shAAV-262432
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Itga5.

shAAV-262432
AAV-m-ITGA5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Itga5 (integrin alpha 5 (fibronectin receptor alpha)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Cd49e; Fnra; VLA5
Description (Vector)
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Gene ID
16402
Gene Name (Vector)
integrin alpha 5 (fibronectin receptor alpha)
Gene Symbol
Itga5
ORF Size (aa)
3162
ORF Size (bp)
3162 bp
RefSeq ID
NM_010577
RefSeq Synonyms
NM_010577, NM_001314041, BC059829, BC050943,
Species
mouse
UniGene ID
Mm.16234

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.