human GMPPB Over-expression AAV

Name 
AAV-h-GMPPB
Cat No 
AAV-210051
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GMPPB.

AAV-210051
AAV-h-GMPPB

Ready-to-use AAV expressing Human GMPPB (GDP-mannose pyrophosphorylase B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MDDGA14; MDDGB14; MDDGC14
Description (Vector)
GMPPB is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
29925
Gene Name (Vector)
GDP-mannose pyrophosphorylase B
Gene Symbol
GMPPB
HGNC ID
HGNC:22932
ORF Size (aa)
1083
ORF Size (bp)
1083 bp
RefSeq ID
NM_013334
RefSeq Synonyms
NM_021971, NM_013334, BC008033, BC001141,
Species
human
UniGene ID
Hs.567488

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.