mouse IL6ST shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Il6st.
shAAV-262193
AAV-m-IL6ST-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Il6st (interleukin 6 signal transducer). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5133400A03Rik; AA389424; BB405851; CD130; D13Ertd699e; gp130
Description (Vector)
Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development (By similarity). The type I OSM receptor is capable of transducing OSM-specific signaling events.
Gene ID
16195
Gene Name (Vector)
interleukin 6 signal transducer
Gene Symbol
Il6st
ORF Size (aa)
2754
ORF Size (bp)
2754 bp
RefSeq ID
NM_010560
RefSeq Synonyms
NM_010560, BC058679,
Species
mouse
UniGene ID
Mm.4364
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.