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mouse IL12RB2 shRNA silencing AAV

Name 
AAV-m-IL12RB2-shRNA
Cat No 
shAAV-262101
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Il12rb2.

shAAV-262101
AAV-m-IL12RB2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Il12rb2 (interleukin 12 receptor, beta 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A930027I18Rik; Ifnm; IL-12RB2
Description (Vector)
Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Gene ID
16162
Gene Name (Vector)
interleukin 12 receptor, beta 2
Gene Symbol
Il12rb2
ORF Size (aa)
2625
ORF Size (bp)
2625 bp
RefSeq ID
NM_008354
RefSeq Synonyms
NM_008354, NM_001311141, BC137745,
Species
mouse
UniGene ID
Mm.188337

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.