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mouse IFITM1 shRNA silencing AAV

Name 
AAV-m-IFITM1-shRNA
Cat No 
shAAV-261890
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ifitm1.

shAAV-261890
AAV-m-IFITM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ifitm1 (interferon induced transmembrane protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110036C17Rik; DSPA2a; Mil-2; Mil2
Description (Vector)
IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.
Gene ID
68713
Gene Name (Vector)
interferon induced transmembrane protein 1
Gene Symbol
Ifitm1
ORF Size (aa)
321
RefSeq ID
NM_026820
RefSeq Synonyms
NM_026820, NM_001112715, BC090972, BC090258, BC027285,
Species
mouse
UniGene ID
Mm.175661

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.