human GLO1 Over-expression AAV

Name 
AAV-h-GLO1
Cat No 
AAV-209980
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human GLO1.

AAV-209980
AAV-h-GLO1

Ready-to-use AAV expressing Human GLO1 (glyoxalase I). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
aldoketomutase; epididymis secretory protein Li 74; GLOD1; glx I; GLYI; glyoxalase domain containing 1; Glyoxalase I; HEL-S-74; ketone-aldehyde mutase; lactoyl glutathione lyase; lactoylglutathione lyase; methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase
Description (eCommerce)
Glyoxylase I is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione [taken from NCBI Entrez Gene (Gene ID: 2739)].
Description (Vector)
The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.
Gene ID
2739
Gene Name (eCommerce)
glyoxalase I
Gene Name (Vector)
glyoxalase I
Gene Symbol
GLO1
HGNC ID
HGNC:4323
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
555
Protein Name (eCommerce)
Lactoylglutathione lyase
RefSeq ID
NM_006708
RefSeq Synonyms
NM_006708, BC015934, BC011365, BC001741,
Research Areas
Apoptosis,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Glyoxylase I is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione [taken from NCBI Entrez Gene (Gene ID: 2739)].
UniGene ID
Hs.268849
UniProt ID (eCommerce)
Q04760

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.