mouse HIVEP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Hivep1.
shAAV-261422
AAV-m-HIVEP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Hivep1 (human immunodeficiency virus type I enhancer binding protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cryabp1
Description (Vector)
This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.
Gene ID
110521
Gene Name (Vector)
human immunodeficiency virus type I enhancer binding protein 1
Gene Symbol
Hivep1
ORF Size (aa)
8064
ORF Size (bp)
8064 bp
RefSeq ID
NM_007772
RefSeq Synonyms
NM_007772, BC156925, BC148370,
Species
mouse
UniGene ID
Mm.4808
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.