mouse HIRA shRNA silencing AAV

Name 
AAV-m-HIRA-shRNA
Cat No 
shAAV-261312
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Hira.

shAAV-261312
AAV-m-HIRA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Hira (histone cell cycle regulator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA138857; D16Ertd95e; Gm15797; N28177; OTTMUSG00000026264; Tuple1
Description (Vector)
Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Gene ID
15260
Gene Name (Vector)
histone cell cycle regulator
Gene Symbol
Hira
ORF Size (aa)
3048
ORF Size (bp)
3048 bp
RefSeq ID
NM_010435
RefSeq Synonyms
NM_010435, BC156807,
Species
mouse
UniGene ID
Mm.453041

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.