mouse HECW1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Hecw1.
shAAV-261211
AAV-m-HECW1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Hecw1 (HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9330116H24Rik; AV273951; E130207I19Rik; Nedl1
Description (Vector)
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
Gene ID
94253
Gene Name (Vector)
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Gene Symbol
Hecw1
ORF Size (aa)
4776
ORF Size (bp)
4776 bp
RefSeq ID
NM_001081348
RefSeq Synonyms
NM_001081348, BC157040, BC156260,
Species
mouse
UniGene ID
Mm.125298
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.