mouse GRPEL2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Grpel2.
shAAV-260803
AAV-m-GRPEL2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Grpel2 (GrpE-like 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mt-GrpE#2; mt-Grpel2
Description (Vector)
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity).
Gene ID
17714
Gene Name (Vector)
GrpE-like 2, mitochondrial
Gene Symbol
Grpel2
ORF Size (aa)
675
ORF Size (bp)
675 bp
RefSeq ID
NM_021296
RefSeq Synonyms
NM_021296, BC120747, BC068232,
Species
mouse
UniGene ID
Mm.269657
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.