mouse GRIK2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Grik2.
shAAV-260762
AAV-m-GRIK2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Grik2 (glutamate receptor, ionotropic, kainate 2 (beta 2)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW124492; GluK2; Glur-6; Glur6; Glurbeta2
Description (Vector)
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus. Modulates cell surface expression of NETO2 (By similarity).
Gene ID
14806
Gene Name (Vector)
glutamate receptor, ionotropic, kainate 2 (beta 2)
Gene Symbol
Grik2
ORF Size (aa)
2610
ORF Size (bp)
2610 bp
RefSeq ID
NM_010349
RefSeq Synonyms
NM_010349, NM_001111268, BC160298,
Species
mouse
UniGene ID
Mm.332838
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.